This snippit of code will restart/reload your python/pygtk app when you log out so you don’t have to keep restarting it.
import gnome.ui
gnome.program_init('program name', "1.0")
client = gnome.ui.master_client()
command = os.path.normpath(os.path.join(os.getcwd(), sys.argv[0]))
client.set_restart_style(gnome.ui.RESTART_IF_RUNNING)
try: client.set_restart_command([command] + sys.argv[1:])
except TypeError:
client.set_restart_command(len(sys.argv), [command] + sys.argv[1:])
client.connect('die', gtk.main_quit)